| Issue |
Radioprotection
Volume 11, Number 1, Janvier-Mars 1976
|
|
|---|---|---|
| Page(s) | 19 - 34 | |
| DOI | https://doi.org/10.1051/radiopro/19761101019 | |
| Published online | 20 August 2017 | |
Forme initiale de la courbe de survie des cellules irradiées(*)
Institut Gustave-Roussy, 16 bis, avenue Paul-Vaillant-Couturier, 94800 Villejuif.
La partie initiale de la courbe de survie correspond aux doses qui intéressent la Radiothérapie et la Protection. Sa forme a un grand intérêt pour l’analyse des mécanismes radiobiologiques de la mort cellulaire. Ce travail discute les différentes formes de courbe de survie qui apparaissent dans les données de la littérature en particulier la pente initiale, les expressions mathématiques de ces courbes, les mécanismes radiobiologiques qu’elles suggèrent.
Abstract
The initial part of cell survival curves is related to doses of interest to Radiotherapy and Radiation Health Protection. Their shape provides a valuable approach to the fundamental mechanisms of cell killing by radiation. In this paper the different shapes of cell survival curves after the published data and the initial slope particularly, the mathematical expressions related to these curves, the radiobiological mechanisms suggested by the shapes of the curves, are discussed.
© DUNOD 1976
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