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Table 4

Linear regression analysis for cumulative entrance skin dose in neonates.

Univariable   Multivariable  


 Variable B (95% CI) p-value B (95% CI) p-value
Birth weight (g)        
   ≤ 750 0.00 (Reference)   0.00 (Reference)  
   751 to ≤ 1000 −0.59 (−0.96, 0.22) 0.002 −0.3 (−0.63, 0.04) 0.081
   1001 to ≤ 1250 −1.11 (−1.45,−0.76) < 0.001 −0.31 (−0.67, 0.05) 0.095
   1251 to ≤ 1500 −1.58 (−1.92,−1.25) < 0.001 −0.5 (−0.88,−0.11) 0.011
Male 0.16 (−0.06, 0.38) 0.15    
Gestational age (weeks) −0.22 (−0.26, −0.19) < 0.001    
Delivery by C-section 0.05 (−0.26, 0.36) 0.756    
Apgar score at 1 minute −0.14 (−0.19, −0.08) < 0.001 0.03 (−0.02, 0.07) 0.237
Apgar score at 5 minutes −0.2 (−0.28, −0.13) < 0.001    
RDS 0.94 (0.72, 1.16) < 0.001 0.44 (0.24, 0.65) < 0.001
PDA 0.6 (0.39, 0.8) < 0.001    
BPD 1.05 (0.88, 1.23) < 0.001    
BPD severity        
   Normal 0.00 (Reference)   0.00 (Reference)  
   Mild 0.85 (0.67, 1.04) < 0.001 0.5 (0.27, 0.72) < 0.001
   Moderate 1.43 (1.15, 1.71) < 0.001 0.8 (0.45, 1.14) < 0.001
   Severe 1.71 (1.26, 2.16) < 0.001 0.91 (0.39, 1.43) 0.001
EONS 0.79 (−0.38, 1.96) 0.182    
LONS 0.79 (0.46, 1.11) < 0.001    
NEC 0.73 (0.46, 1) < 0.001    
IVH 0.79 (0.49, 1.09) < 0.001    
ROP 0.86 (0.64, 1.08) < 0.001    
Pneumothorax 0.75 (0.2, 1.3) 0.008    
PVL 0.21 (−0.54, 0.95) 0.586    
Duration of ventilation (days) 0.03 (0.03, 0.04) < 0.001 0.01 (0, 0.02) 0.008
Duration of TPN (days) 0.04 (0.03, 0.04) < 0.001    
Duration of C- line (days) 0.04 (0.03, 0.04) < 0.001    

The cumulative entrance skin dose (dependent variable) was log-transformed before linear regression analysis.

B: regression coefficient; CI: confidence interval; RDS: respiratory distress syndrome; PDA: patent ductus arteriosus; BPD: bronchopulmonary dysplasia; EONS: early-onset sepsis; LONS: late-onset sepsis; NEC: necrotizing enterocolitis; IVH: intraventricular hemorrhage; ROP: retinopathy of prematurity; PVL: periventricular leukomalacia; TPN: total parenteral nutrition.

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