Article

Investigation of the effects of gamma radiation on plasma levels of Zn, Cu, Mn and Se in nuclear medicine staff

¹ Department of Medical Radiation Engineering, Central Tehran Branch, Islamic Azad University, Tehran, Iran
² Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran

^* Corresponding authors: m.s.barough@gmail.com; beigiharchegani.a@gmail.com

Received: 21 April 2018
Accepted: 15 December 2018

Abstract

We assessed possible changes in the levels of some trace elements among nuclear medicine staff. This study was carried out on 30 nuclear medicine staff and 10 individuals as a control group. After the blood samples were collected, serum levels of trace elements were measured using atomic absorption spectroscopy (AAS). Mean Zn levels in the control group (89.75 ± 17.35 µmol/l) were significantly (p = 0.002) higher than in the exposed group (70.91 ± 14.46 µmol/l). Increased duration of exposure was significantly associated with reduced zinc levels (p = 0.005). Furthermore, the 5-year average dose received was adversely and significantly correlated with zinc concentrations (p = 0.019). No significant difference was observed in the Cu level between control group (93.85 ± 25.33 µmol/l) and staff worker group (85.6 ± 21.66 µmol/l) (p = 0.32). A positive significant correlation was observed between exposure time and reduced Cu levels (p = 0.05). No difference was found in mean Mn and Se levels between both groups according to exposure time. Declined Zn and Cu levels may be considered as one of the possible mechanisms of oxidative damages induced by gammas rays. Therefore, an antioxidant treatment could be recommended for people who work in medical radiation centers.