| Issue |
Radioprotection
Volume 51, Number 2, April-June 2016
|
|
|---|---|---|
| Page(s) | 101 - 111 | |
| DOI | https://doi.org/10.1051/radiopro/2016019 | |
| Published online | 26 May 2016 | |
Article
3D imaging of the elemental concentration associated with a malignant tumor in breast cancer using Neutron Stimulated Emission Computed Tomography: a Monte Carlo simulation study
Physics Department, College of Sciences, Ferdowsi
University of Mashhad, 91775-1436, Mashhad, Islamic Republic of
Iran.
Received:
8
July
2015
Accepted:
4
March
2016
Three-dimensional imaging of a cancerous breast with NSECT was proposed for the first time in this study. An irradiation system in a clinically relevant situation was simulated using the MCNP code. In the reconstructed images, the location and boundary of the tumor were identified by four elements, especially by 39K, with the ratio of malignant to healthy pixel intensity of about 2.446 (p-value ≪ 0.01). The average glandular dose was lower than the reference levels, and was comparable with the dose of digital X-ray mammography and 3D tomosynthesis examinations.
Key words: neutron stimulated emission computed tomography / breast cancer imaging / early diagnosis / Monte Carlo simulation / MLEM reconstruction
© EDP Sciences, 2016
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