Issue |
Radioprotection
Volume 47, Number 1, Janvier-Mars 2012
|
|
---|---|---|
Page(s) | 119 - 148 | |
Section | Meeting Report | |
DOI | https://doi.org/10.1051/radiopro/2011162 | |
Published online | 21 March 2012 |
DoReMi workshop on multidisciplinary approaches to evaluating cancer risks associated with low-dose internal contamination
Approches multidisciplinaires pour l’évaluation du risque de cancer associé aux contaminations internes aux faibles doses : synthèse du séminaire scientifique organisé dans le cadre du projet européen DoReMi
1
Institut de radioprotection et de sûreté nucléaire,
IRSN, Fontenay-aux-Roses
Cedex, France
2
Belgian Nuclear Research Centre, SCK-CEN, Mol,
Belgium
3
Health Protection Agency, Centre for Radiation Chemical and
Environmental Hazards, HPA-CRCE, Chilton, UK
4
Centre for Research in Environmental Epidemiology,
CREAL, Barcelona,
Spain
5
Federal Office for Radiation Protection, Department of Radiation
Protection and Health, BfS, Neuherberg, Germany
6
Inserm U612, Institut Curie, Orsay, France
7
International Agency for Research on Cancer, Section of
Environment and Radiation, IARC, Lyon, France
Received: 29 November 2011
Accepted: 13 December 2011
A workshop dedicated to cancer risks associated with low-dose internal contamination was organised in March 2011, in Paris, in the framework of the DoReMi (Low Dose Research towards Multidisciplinary Integration) European Network of Excellence. The aim was to identify the best epidemiological studies that provide an opportunity to develop a multidisciplinary approach to improve the evaluation of the cancer risk associated with internal contamination. This workshop provided an opportunity for in-depth discussions between researchers working in different fields including (but not limited to) epidemiology, dosimetry, biology and toxicology. Discussions confirmed the importance of research on the health effects of internal contamination. Several existing epidemiological studies provide a real possibility to improve the quantification of cancer risk associated with internal emitters. Areas for future multidisciplinary collaborations were identified, that should allow feasibility studies to be carried out in the near future. The goal of this paper is to present an overview of the presentations and discussions that took place during this workshop.
Résumé
Un séminaire scientifique dédié à l’étude du risque de cancer associé aux contaminations internes à faibles doses a été organisé à Paris en mars 2011, dans le cadre du réseau d’excellence européen DoReMi (Low Dose Research towards Multidisciplinary Integration). L’objectif était d’identifier les meilleures études épidémiologiques pouvant permettre le développement de collaborations multidisciplinaires afin d’améliorer la quantification des risques associés à une contamination interne. Ce séminaire a été l’occasion de discussions approfondies entre chercheurs de différentes disciplines, telles que l’épidémiologie, la dosimétrie, la biologie et la toxicologie. Ces discussions ont confirmé l’importance des recherches sur les effets sanitaires des contaminations internes. Plusieurs études épidémiologiques existantes présentent une réelle capacité à améliorer les connaissances dans ce domaine. Des pistes de collaborations multidisciplinaires ont été dégagées, qui pourraient déboucher à court terme sur des études de faisabilité. Le but de cet article est de synthétiser les présentations et les discussions qui se sont tenues lors du séminaire.
Key words: Cancer / contamination / internal / epidemiology / dosimetry / radiobiology / toxicity / radiological
© EDP Sciences, 2012
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