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Table 4
Associations of different DNA repair gene polymorphisms with the MN frequencies in the ICs group subdivided by exposure status.
Cardiology staff | Exposure (last year) | Exposure (last 5 years) | ||||
---|---|---|---|---|---|---|
< 3 mSv | ≥ 3 mSv | < 10 mSv | ≥ 10 mSv | |||
XRCC1 codon 194 |
W(n) | 23.6 ± 12.0* (54) |
40.2 ± 24.5 (23) | 25.5 ± 14.2 (53) |
35.3 ± 24.1 (24) |
|
M(n) | 22.3 ± 5.2 (6) |
21.6 ± 5.9** (6) |
22.5 ± 5.4 (8) |
21.0 ± 5.7 (4) |
||
p value | p < 0.0005* p = 0.04** |
NS |
||||
XRCC3 codon 241 |
W(n) | 22.2 ± 9.5* (33) |
32 ± 22.5 (9) |
25.1 ± 12.8 (31) |
22.1 ± 16.4 (12) |
|
V(n) | 25.0 ± 13.6** (27) |
38.4 ± 23.8 (20) |
25.1 ± 14.2 (30) |
40.5 ± 24.0 (17) |
||
p value | p = 0.001* p = 0.01** |
F = 4.5 p = 0.002a |
||||
XPD codon 751 |
W(n) | 23.6 ± 12.4 (28) |
36.0 ± 20.2 (11) |
25.2 ± 15.0 (29) |
32.5 ± 17.2 (10) |
|
V(n) | 23.4 ± 10.9 (32) |
36.6 ± 25.4 (18) |
25.0 ± 11.9 (32) |
33.7 ± 25.9 (18) |
||
p value | F = 3.48 p = 0.019a |
NS |
||||
MSH3 codon 1036 |
W(n) | 16.0 ± 9.2 (6) |
52.0 ± 32.5 (2) |
17.8 ± 9.0* (5) |
37.0 ± 34.6 (3) |
|
V(n) | 24.3 ± 11.5 (54) |
35.2 ± 22.8 (27) |
25.8 ± 13.5 (56) |
32.8 ± 22.0 (25) |
||
p value | F = 5.54 p = 0.002a |
p = 0.044* |
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