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Table 4

Associations of different DNA repair gene polymorphisms with the MN frequencies in the ICs group subdivided by exposure status.

Cardiology staff Exposure (last year) Exposure (last 5 years)


< 3 mSv ≥ 3 mSv < 10 mSv ≥ 10 mSv
XRCC1
codon 194
W(n) 23.6 ± 12.0*
(54)
40.2 ± 24.5 (23) 25.5 ± 14.2
(53)
35.3 ± 24.1
(24)
M(n) 22.3 ± 5.2
(6)
21.6 ± 5.9**
(6)
22.5 ± 5.4
(8)
21.0 ± 5.7
(4)
p value p < 0.0005*
p = 0.04**
 
NS
 
XRCC3
codon 241
W(n) 22.2 ± 9.5*
(33)
32 ± 22.5
(9)
25.1 ± 12.8
(31)
22.1 ± 16.4
(12)
V(n) 25.0 ± 13.6**
(27)
38.4 ± 23.8
(20)
25.1 ± 14.2
(30)
40.5 ± 24.0
(17)
p value p = 0.001*
p = 0.01**
 
F = 4.5     p = 0.002a
 
XPD
codon 751
W(n) 23.6 ± 12.4
(28)
36.0 ± 20.2
(11)
25.2 ± 15.0
(29)
32.5 ± 17.2
(10)
V(n) 23.4 ± 10.9
(32)
36.6 ± 25.4
(18)
25.0 ± 11.9
(32)
33.7 ± 25.9
(18)
p value F = 3.48
p = 0.019a
 
NS
 
MSH3
codon 1036
W(n) 16.0 ± 9.2
(6)
52.0 ± 32.5
(2)
17.8 ± 9.0*
(5)
37.0 ± 34.6
(3)
V(n) 24.3 ± 11.5
(54)
35.2 ± 22.8
(27)
25.8 ± 13.5
(56)
32.8 ± 22.0
(25)
p value F = 5.54
p = 0.002a
 
p = 0.044*

W: wild type, V: variant type. *or ** Mean ± SD vs. bold variable is significant at the 0.05 level by least significant difference (LSD) post hoc test.

a

ANOVA p value among groups.

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