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Table 2
General characteristics and genotype distributions of studied genes in the ICS and control groups.
| ICsa | Control | p value | |
|---|---|---|---|
| Gender, n (%) | |||
| Male | 58 (65.2) | 27 (67.5) | 0.48 |
| Female | 31 (34.8) | 13 (32.5) | |
| Mean age, years ± S.D. | 41.5 ± 7.5 | 41.4 ± 9.0 | 0.93 |
| Smoking habits, n (%) | |||
| Yes | 3 (3.5) | 4 (10.0) | 0.13 |
| No | 83 (96.5) | 36 (90.0) | |
| Mean time exposure, years ± S.D. | 9.5 ± 6.7 | 13.8 ± 7.7 | 0.21 |
| Mean last year exposure mSv ± SD | 3.5 ± 3.4 | – | |
| Mean last five years exposure mSv ± SD | 11.1 ± 10.0 | – | |
| Mean MN frequency ± SD (‰) | 27.7 ± 17.2 (89) | 8.0 ± 2.6 (40) | < 0.0005 |
| Nuclear division index (NDI) | 1.7 ± 0.1 | 1.7 ± 0.1 | 0.32 |
| XRCC1 codon 194, n (%) | 0.82 | ||
| Wild: Arg/Arg | 77 (86.5) | 34 (85) | |
| Variant: Trp/ Trp | 0 | 0 | |
| Variant: Arg/ Trp | 12 (13.5) | 6 (15) | |
| XRCC3 codon 241, n (%) | 0.72 | ||
| Wild: Thr/ Thr | 42 (47.2) | 17 (42.5) | |
| Variant:Met/Met | 11 (12.4) | 7 (17.5) | |
| Variant: Thr/Met | 36 (40.4) | 16 (40) | |
| XPD codon 751, n (%) | 0.003 | ||
| Wild: Lys/Lys | 39 (43.8) | 7 (17.5) | |
| Variant:Gln/Gln | 16 (18.0) | 17 (42.5) | |
| Variant: Lys/ Gln | 34 (38.2) | 16 (40) | |
| MSH3 codon 1036, n (%) | 0.4 | ||
| Wild: Ala/ Ala | 8 (9.0) | 1 (2.5) | |
| Variant :Thr/ Thr | 50 (56.2) | 25 (62.5) | |
| Variant: Ala/ Thr | 31 (34.8) | 14 (35.0) |
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