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Table 4

Effective half-lives of radionuclides considered in this study.

Radionuclide Effective half-life considered (days) Reference
phosphorus-32 14.3 (physical half-life)
strontium-89 50.7 (physical half-life)
yttrium-90 2.7 (physical half-life)
indium-111 0.6 (Jones, 2004)
iodine-131:
Thyroid non-cancer
MIBG
Lipiocis®
Thyroid cancer

5.2
2.0
5.5
0.9

(Jones, 2004; U.S. NRC, 2020)
(Jones, 2004; Petyt et al., 2009; CIS bio international, 2017)
(Jones, 2004; CIS bio international, 2006)
(Venencia et al., 2002; Jones, 2004)
samarium-153 1.95 (physical half-life)
holmium-166 1.1 (physical half-life) Not concerned because the microspheres are considered with no biological elimination
lutetium-177:
Lutathera®
PSMA

1.0
2.1

(Calais et al., 2014; EMA, 2021)
(Kurth et al., 2018)
erbium-169 9.4 (physical half-life)
rhenium-186 3.8 (physical half-life)
radium-223 11.4 (physical half-life) No reference found in literature. Only the physical half-life was considered, in a conservative approach
actinium-225 10 (physical half-life) No reference found in literature. Only the physical half-life was considered, in a conservative approach

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